Cancer metabolism Lab
The group is focused on the intricate metabolic interplay between cancer and the immune system. Specifically, they investigate the role of mitochondrial function and amino acid metabolism in modulating cancer growth and immune evasion.
The work seeks to elucidate the mechanisms by which cancer cells manipulate mitochondrial metabolism to subvert immune responses. This includes examining how cancer cells compete with immune cells for essential nutrients within the tumor microenvironment, and how they utilize metabolites and signaling molecules to suppress immune cell activity.
The ultimate goal of this research is to identify novel therapeutic strategies that target cancer cell metabolism, thereby disrupting cancer cell energetics and enhancing the immune system’s capacity to recognize and eliminate malignant cells.
Keywords
Mitochondrial Metabolism; Immune Escape; Cancer Aggressiveness; Amino Acid Metabolism;Tumor Microenvironment.
GROUP MEMBERS
Alessio Menga
Group Leader
Associate Professor
Roberta Basile
PhD Student
Chiara Donno
PhD Student
For any information, please contact
corefacilities.ipazia@uniupo.it
or segreteria.caad@uniupo.
CAAD
Center for Translational Research on
Autoimmune and Allergic Disease
Centro di Ricerca Traslazionale
sulle Malattie Autoimmuni e Allergiche
Corso Trieste 15/A
Novara – 28100 (ITALY)
Cancer metabolism Lab
The group is focused on the intricate metabolic interplay between cancer and the immune system. Specifically, they investigate the role of mitochondrial function and amino acid metabolism in modulating cancer growth and immune evasion.
Keywords
Mitochondrial Metabolism; Immune Escape; Cancer Aggressiveness; Amino Acid Metabolism;Tumor Microenvironment.
The work seeks to elucidate the mechanisms by which cancer cells manipulate mitochondrial metabolism to subvert immune responses. This includes examining how cancer cells compete with immune cells for essential nutrients within the tumor microenvironment, and how they utilize metabolites and signaling molecules to suppress immune cell activity.
The ultimate goal of this research is to identify novel therapeutic strategies that target cancer cell metabolism, thereby disrupting cancer cell energetics and enhancing the immune system’s capacity to recognize and eliminate malignant cells.
GROUP MEMBERS
Alessio Menga
Group Leader
Associate Professor
Roberta Basile
PhD Student
Chiara Donno
PhD Student
For any information, please contact
corefacilities.ipazia@uniupo.it
or segreteria.caad@uniupo.
CAAD
Center for Translational Research on
Autoimmune and Allergic Disease
Centro di Ricerca Traslazionale
sulle Malattie Autoimmuni e Allergiche
Corso Trieste 15/A
Novara – 28100 (ITALY)